By Bing Yan
Combinatorial chemistry has built quickly some time past decade, with nice advances made through scientists engaged on research and purification of a giant variety of compounds and the research of polymer-bound compounds. although, ambitious demanding situations lie sooner than latest researcher. for instance, high-throughput research and purification applied sciences has to be additional constructed to make sure combinatorial libraries are "purifiable," and "drugable."
To this finish, research and Purification tools in Combinatorial Chemistry describes quite a few analytical suggestions and structures for the improvement, validation, qc, purification, and physicochemical trying out of combinatorial libraries. a brand new quantity in Wiley's Chemical research sequence, this article has 4 elements covering:
* a variety of ways to tracking reactions on sturdy aid and optimizing reactions for library synthesis
* High-throughput analytical equipment used to investigate the standard of libraries
* High-throughput purification techniques
* Analytical tools utilized in post-synthesis and post-purification stages
Drawing from the contributions of revered specialists in combinatorial chemistry, this finished booklet offers insurance of functions of Nuclear Magnetic Resonance (NMR), liquid chromatography/mass spectrometry (LC/MS), Fourier rework Infrared (FTIR), micellar electrokinetic chromatography (MEKC) applied sciences, in addition to different analytical techniques.
This eminently helpful quantity is an important addition to the library of scholars and researchers learning or operating in analytical chemistry, combinatorial chemistry, medicinal chemistry, natural chemistry, biotechnology, biochemistry, or biophysics.
Read Online or Download Analysis and Purification Methods in Combinatorial Chemistry (Chemical Analysis: A Series of Monographs on Analytical Chemistry and Its Applications) PDF
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